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pirl-unc / hitlist / 25202284293
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DEFAULT BRANCH: main
Ran 01 May 2026 04:31AM UTC
Jobs 1
Files 27
Run time 1min
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01 May 2026 04:30AM UTC coverage: 70.945%. Remained the same
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v1.30.25: Register AAV2/6/8 reference proteomes (#213) (#214)

Adds VIRAL_PROTEOMES entries for the three AAV serotypes that have
clean UniProt references:

  Adeno-associated virus 2     760 rows / 4 PMIDs   -> UP000180764
  Adeno-associated virus 6     466 rows / 2 PMIDs   -> UP000119472
  Adeno-associated virus 8      10 rows / 2 PMIDs   -> UP000201958

The "adeno-associated virus - 6" key handles IEDB's hyphen-space-
hyphen variant, which the substring matcher would otherwise miss.

AAV1 (8 rows) and AAV9 (585 rows) deliberately remain unregistered:
- UniProt has no clean serotype-9 reference proteome (UniProt-side
  gap) -- AAV9's ~585 rows stay blocked until a custom FASTA is
  added or UniProt publishes one
- UniProt's AAV1 hit (UP000232962) resolves to "California sea lion
  AAV1", which is the wrong organism for the human gene-therapy /
  immunopeptidome context the IEDB rows come from. Registering it
  would route 8 rows to the wrong proteome.

Total ~1.2K rows / ~8 PMIDs unblocked. After this PR the
warn-severity gaps from qc.proteome_coverage drop from 5 to 2
(the "" and "unidentified" buckets, which are a different problem
-- IEDB binding rows that don't carry a source organism).

3709 of 5228 relevant lines covered (70.94%)

0.71 hits per line

Coverage Regressions

Lines Coverage ∆ File
106
38.33
0.0% downloads.py
Jobs
ID Job ID Ran Files Coverage
1 25202284293.1 01 May 2026 04:31AM UTC 27
70.94
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