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pirl-unc / hitlist / 27284581603
80%

Build:
DEFAULT BRANCH: main
Ran 10 Jun 2026 02:51PM UTC
Jobs 1
Files 29
Run time 1min
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10 Jun 2026 02:47PM UTC coverage: 79.956%. Remained the same
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v1.36.1: HPA-vet CTA panel; resolve COG-N-471nb CVCL; label MAPTAC mixture (#325)

(a) COG-N-471nb -> CVCL_LF60 (Cellosaurus catalogues it under the full name
    with the 'nb' suffix; human pediatric neuroblastoma, Harenza 2017).

(b) Abelin 2019 MAPTAC class-I/II rows (PMID 31495665) were 'MAPTAC' (a method,
    not a cell) -> '(unspecified type)'. They're a mono-allelic pulldown over a
    CELL-LINE MIXTURE (A375 + Expi293 + HEK293 + HeLa); relabel cell_name
    'cell-line mixture' so --by-tissue shows the mixture honestly. (A gene's
    peptide derives from whichever host expresses it — PRAME from A375.)

CTA panel: vetted against the Human Protein Atlas (there was no HPA filter; the
set was hand-curated, so MAGE-D slipped in). Keep only germline/reproductive-
RESTRICTED genes (Tissue/Group enriched in testis/placenta/epididymis AND
Detected in single/some). Removes broadly-expressed false positives ODF2 (the
one that topped the rollup, like MAGE-D), ACRBP, CABYR, OIP5, SPA17, DDX43,
PIWIL2, IL13RA2, MAGEC3, GAGE1, PAGE4, BAGE/2. Adds the missing testis-restricted
GAGE paralogs (GAGE2A/2E, GAGE12B-J, GAGE13) + completes MAGE/SSX/SPANX/PAGE
families. 68 -> 83 genes, all HPA-grounded; criterion + exclusions documented in
gene_sets.yaml.

5473 of 6845 relevant lines covered (79.96%)

0.8 hits per line

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ID Job ID Ran Files Coverage
1 27284581603.1 10 Jun 2026 02:51PM UTC 29
79.96
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Source Files on build 27284581603
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