27288234003
77%

Ran 10 Jun 2026 03:51PM UTC

Jobs 1

Files 37

Run time 1min

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Committed 10 Jun 2026 03:49PM UTC coverage: 74.119%. Remained the same

Build # 27288234003

Build Type

push

github

Committed by

web-flow

Commit Message

Add GAGE10 to CTA universe; exclude fragment-model GAGE12B (tsarina#108) (#109)

* Add GAGE10 to CTA universe; exclude fragment-model GAGE12B (tsarina#108)

GAGE10 (ENSG00000215274) is a full-length GAGE paralog (116 aa, 5 exons)
missing from the bundled universe, with clean testis restriction on HPA
bulk. Added via add_cta_gene.py (passes_filters=True, restriction=TESTIS).
testis 1.6 nTPM < 2.0 floor so never_expressed=True; included for
non-CTA negative-set completeness. Filtered-set guard 285 -> 286.

GAGE12B (ENSG00000236737) deliberately held out: that Ensembl ID is a
degenerate 117-bp 3'-stub (7-aa ORF = shared GAGE C-terminus), not a
GAGE protein. Its HPA somatic signal is background on a malformed model,
not paralog multimapping. See tsarina#108.

Version: 1.10.0 -> 1.12.0 (1.11.0 reserved by in-flight PR #107).

* Address review: pin GAGE10/GAGE12B by identity, not just count (tsarina#108)

The count guard alone would pass if a different gene swapped in for GAGE10.
Add test_gage10_added_gage12b_excluded asserting the two GAGE-audit
decisions by identity: GAGE10 in the filtered set but not the expressed set
(never_expressed, 1.6 < 2.0 floor); GAGE12B in neither (fragment model).

Coverage Stats

2692 of 3632 relevant lines covered (74.12%)

0.74 hits per line

Jobs

ID	Job ID	Ran	Files	Coverage
1	27288234003.1	10 Jun 2026 03:51PM UTC	37	74.12	GitHub Action Run

pirl-unc / tsarina / 27288234003
77%

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