biocore / deblur / 391 / 1

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fix lower case nucleotides (#168)

* added a unit test to check that all deblurred fragments are all uppercase

* test mix case handling for function create_otu_table

* fixing flake8

* flake8

* to upper case

* enforce upper case sequences and collapse counts for mix cases

161 of 183 branches covered (87.98%)

454 of 512 relevant lines covered (88.67%)

0.89 hits per line