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[ADAM-1358] Refactor BQSR to improve performance and legibility. Resolves #1358. * Adds instrumentation to BQSR. * Changed SnpTable to remove RichVariant conversion, use VariantRDD API. * Refactoring SnpTable to eliminate per-residue costly masked site lookup. * Restructuring core of SnpTable around an array to improve GC performance. Additionally, wrote custom serializer to improve serialization performance. * Added test suite for SnpTable, to test table creation. * Refactored SnpTable to use an IntervalArray-like approach. This approach improves masked site lookup performance by 50%. * Added tests to SnpTableSuite to cover lookup case, and reenabled tests in BaseQualityRecalibrationSuite. * Adding unit test coverage to covariates * Revert "[ADAM-775] Allow all IUPAC codes in BQSR" This reverts commit 207eebaf3. * Pulled Seq allocation for base check out into an immutable set. * Rewrote dinuc covariate. 50% improvement in performance. * Rewrite main BQSR aggregate as reduce by key * Added tests to recalibrator, recalibration table. * Majorly refactors of BQSR tables. * Starting to factor out the QualityScore class * Refactoring CovariateKey to reduce size in memory * Eliminated `org.bdgenomics.adam.rich.DecadentRead` (partially resolves #577) * Refactor CovariateKey to store record group ID instead of record group name. * Removed `org.bdgenomics.adam.models.QualityScore`. * Split multi-class files into one class per file (excepting private classes) to improve navigability. * Scaladoc all the recalibrators! You get a scaladoc! And you get a scaladoc!
4695 of 5826 relevant lines covered (80.59%)
0.81 hits per line
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