26858867000
82%

Ran 03 Jun 2026 01:53AM UTC

Jobs 4

Files 36

Run time 1min

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Committed 03 Jun 2026 01:50AM UTC coverage: 80.859% (+0.02%) from 80.842%

Build # 26858867000

Build Type

push

github

Committed by

web-flow

Commit Message

Curated signature guidance + RNA reproducibility map (#145) (#156)

The signature set itself landed across #141/#142/#144; this encodes the
honest map of what each signature is good for, so users don't reach for RNA
where the sequence (Pgen/Ppost, #143) is the right tool.

- SIGNATURE_GUIDANCE: queryable per-signature usage map (tier in
  recommended/situational/wrong_biology, use_for, reproducibility note).
  Differentiated + AcuteActivation are the donor-reproducible axes;
  TumorReactive is flagged wrong-biology for short PBMC culture.
- recommended_signatures() helper + RNA_REPRODUCIBILITY_NOTE constant
  (RNA does NOT reproducibly recover the precursor/cross-reactivity axis;
  use sequence features; don't overfit signatures on n=2 donors).
- docs/reproducibility_map.md + nav.

Bump 2.25.0.

Coverage Stats

8166 of 10099 relevant lines covered (80.86%)

3.23 hits per line

Coverage Regressions

Lines	Coverage	∆	File
8	95.58	0.23%	signature_methods.py

Jobs

ID	Job ID	Ran	Files	Coverage
1	python-3.12 - 26858867000.1	03 Jun 2026 01:53AM UTC	36	80.85	GitHub Action Run
2	python-3.11 - 26858867000.2	03 Jun 2026 01:53AM UTC	36	80.85	GitHub Action Run
3	python-3.10 - 26858867000.3	03 Jun 2026 01:53AM UTC	36	80.85	GitHub Action Run
4	python-3.9 - 26858867000.4	03 Jun 2026 01:53AM UTC	36	80.81	GitHub Action Run

pirl-unc / tcrsift / 26858867000
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pirl-unc / tcrsift / 26858867000 82%

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