26841812559

Committed 02 Jun 2026 07:04PM UTC coverage: 81.522% (+0.09%) from 81.433%

Build # 26841812559

Build Type

push

github

Committed by

web-flow

Commit Message

2.19.0: gene signatures as selection methods, wired into run (#140)

Signed gene signatures (genes_up/genes_down, focal/broad panels) scored as z-score of log(1+TPM) then mean across genes; gap/otsu/quantile cutoffs (gap returns none when no distinct cluster). Panels: Proliferation/Cytolytic/Differentiated (+Broad), TumorReactive, AntigenExperienced, AIM/AIMBroad, CirculatingMemory. selection.signatures wires them into run (scored on adata.X, injected as synthetic methods feeding the rules). Strict: a missing signature gene errors (no silent partial scoring). No context guards — caveats are documentation.

Coverage Stats

7937 of 9736 relevant lines covered (81.52%)

3.26 hits per line

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58.29

/cli.py

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pirl-unc / tcrsift / 26841812559

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