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Add ReferenceSegment extension to MutantTranscript (#252) (#332)

``MutantTranscript`` now supports two shapes:

* **Point-variant shape** (``reference_transcript`` set, existing
  behaviour) — a single reference transcript with edits applied.
  Unchanged for the protein-diff annotator's SNV / MNV / indel path.

* **Structural-variant shape** (``reference_segments`` set) — an
  ordered tuple of :class:`ReferenceSegment` objects that assemble
  into the mutant cDNA when concatenated. A gene fusion is two
  segments from two transcripts; a translocation to intergenic is
  one transcript segment plus a genomic-interval segment; an
  inversion is three forward / reverse / forward segments.

``ReferenceSegment`` carries ``source`` (any object exposing
``sequence`` — :class:`pyensembl.Transcript`, ``GenomicInterval``,
a patient-specific contig from a personalized assembly, or a
long-read-derived local assembly wrapper), ``start`` / ``end``
slice coordinates, ``strand``, and an optional label.

Deliberately open source typing so the SV annotator (PR 10) can
plug in:
* personalized / full-genome references (same ``genome=`` hook as
  today's point variants)
* long-read-derived rearranged alleles via ``alt_assembly`` on
  :class:`StructuralVariant` (wrapped as a synthetic segment)
* RNA-evidence-scored segment variants via the ``Outcome.evidence``
  dict from PR 7

Backwards-compatible: existing callers (``apply_variant_to_transcript``
and ``splice_outcomes``) pass ``reference_transcript=`` by keyword
and keep working unchanged. Validation raises if neither shape is
populated.

Bump version to 4.4.0 for the new public type.
Source Files on build 24673406583
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